Background Obesity results from an imbalance between energy intake and expenditure. In rodents and newborn humans, brown adipose tissue helps regulate energy expenditure by thermogenesis mediated by the expression of uncoupling protein 1 (UCP1), but brown adipose tissue has been considered to have no physiologic relevance in adult humans.

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Matthew Broderick, Actor: The Producers. A slight comic actor chiefly known for his manish charm, Matthew Broderick was born on March 21, 1962 in New York City, to Patricia Broderick (née Biow), a playwright …

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